comments with qualifications... been a long time since I shot a wheel gun in competition, but when I did it was for a longer cartridge (.357mag) using speed loaders, and a shorter .45acp with moon clips... naturally the shorter cartridge was easier to load with the moon clips...in those days Ranch Products was about the only supplier of clips for the M25... if a clip was bent, and it was easy to do when loading and unloading the clips, it would cause cylinder drag... additionally I had to mill about .025" off the nose of the hammer (firing pin on nose) of the M25 to reliably reach the primers as they were springy in the clips...I'm sure the clip technology, as well as SW in frame firing pin location has eliminated these problems
Alf should have more timely comments.. as I think he shoots one of those archaic wheely thingies